A new semi-empirical wind turbine capacity factor for maximizing annual electricity and hydrogen production

The capacity factor is an important wind turbine parameter which is ratio of average output electrical power to rated electrical power of the wind turbine. Another main factor, the AEP, the annual energy production, can be determined using wind characteristics and wind turbine performance. Lower rated power may lead to higher capacity factor but will reduce the AEP. Therefore, it is important to consider simultaneously both the capacity factor and the AEP in design or selecting a wind turbine. In this work, a new semi-empirical secondary capacity factor is introduced for determining a rated wind speed at which yearly energy and hydrogen production obtain a maximum value. This capacity factor is expressed as ratio of the AEP for wind turbine to yearly wind energy delivered by mean wind speed at the rotor swept area. The methodology is demonstrated using the empirical efficiency curve of Vestas-80 2 MW turbine and the Weibull probability density function. Simultaneous use of the primary and the secondary capacity factors are discussed for maximizing electrical energy and hence hydrogen production for different wind classes and economic feasibility are scrutinized in several wind stations in Kuwait.     

网络安全威胁因素及其常见网络安全技术分析

社会经济的快速发展促进了科学技术水平的显著提升，社会生产生活各个领域当中对计算机网络的应用程度不断提升，当前，网络已经成为了人们日常生活与工作的重要组成部分。为此，加强对网络安全等因素影响研究就显得格外重要。网络环境关系着用户的使用质量，更加影响人们的工作效率，加强对网络安全技术的研究时解决相关问题的核心内容。本文针对网络安全威胁因素以及常见的网络安全技术进行了简要分析。     

基于因子分析法的地区财政支出状况评价

以2012年我国财政支出数据为依据进行建模分析，并对我国目前各地财政支出状况给出科学的解释和说明。财政支出是一种经济行为，财政支出结构对于一个国家的经济发展起着至关重要的影响。运用因子分析法算出因子得分，对我国财政支出数据进行分析发现：我国各地区财政支出仍然相当不平衡，要实行财政转移以缩小各地财力差异。     

Classification of quasigroups based on period factors

Edon80 is a stream cipher design that had advanced to the third and last phase of the eSTREAM project. The core of the cipher consists quasigroup string e-transformations and it employs four quasigroups of order 4. The employed quasigroups have influence on the period of the keystream. There are 576 quasigroups of order 4 in total which have different period factors. The four quasigroups used in Edon80 were chosen by numerous computer experiments. In this paper, based on permutation groups, we give a theory criterion for the determination of quasigroups and give a complete classification for the 576 quasigroups of order 4 according to their period factors.     

Reduction of Ripple Current Loss by Electromagnetic Coupling of Air‐Core Reactors

To reduce the loss due to ripple current in a multiphase current‐reversible chopper, we investigated electromagnetic coupling of an air‐core reactor. We derived the relationship between the amplitude of the ripple current, the duty factor, and the electromagnetic coupling coefficient, and used the results to estimate the effects of electromagnetic coupling in the design of a train energy storage system. We built reactors with electromagnetic coupling coefficients of 0.93 and 0.60. These reactors employed a new winding structure that provides an optimal electromagnetic coupling coefficient. The mass of the former type of reactor was increased by 4.4% over the conventional design, and that of the latter type of reactor was decreased by 17%. Finally, we tested the new reactors. When the chopper employs the former type of reactor and operates with equal‐phase switching and cumulative coupling, the loss due to ripple current is decreased by 11%. When the chopper employs the latter type of reactor and operates with shift‐phase switching and differential coupling, the loss is decreased to 31%. The test showed that the calculated relationships agreed with the measured values.     

Preliminary Evidence on the Diagnostic and Molecular Role of Circulating Soluble EGFR in Non-Small Cell Lung Cancer

Assessment of biological diagnostic factors providing clinically-relevant information to guide physician decision-making are still needed for diseases with poor outcomes, such as non-small cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) is a promising molecule in the clinical management of NSCLC. While the EGFR transmembrane form has been extensively investigated in large clinical trials, the soluble, circulating EGFR isoform (sEGFR), which may have a potential clinical use, has rarely been considered. This study investigates the use of sEGFR as a potential diagnostic biomarker for NSCLC and also characterizes the biological function of sEGFR to clarify the molecular mechanisms involved in the course of action of this protein. Plasma sEGFR levels from a heterogeneous cohort of 37 non-advanced NSCLC patients and 54 healthy subjects were analyzed by using an enzyme-linked immunosorbent assay. The biological function of sEGFR was analyzed in vitro using NSCLC cell lines, investigating effects on cell proliferation and migration. We found that plasma sEGFR was significantly decreased in the NSCLC patient group as compared to the control group (median value: 48.6 vs. 55.6 ng/mL respectively; p = 0.0002). Moreover, we demonstrated that sEGFR inhibits growth and migration of NSCLC cells in vitro through molecular mechanisms that included perturbation of EGF/EGFR cell signaling and holoreceptor internalization. These data show that sEGFR is a potential circulating biomarker with a physiological protective role, providing a first approach to the functional role of the soluble isoform of EGFR. However, the impact of these data on daily clinical practice needs to be further investigated in larger prospective studies.     

Heat Killed Lactobacillus reuteri GMNL-263 Reduces Fibrosis Effects on the Liver and Heart in High Fat Diet-Hamsters via TGF-β Suppression

Obesity is one of the major risk factors for nonalcoholic fatty liver disease (NAFLD), and NAFLD is highly associated with an increased risk of cardiovascular disease (CVD). Scholars have suggested that certain probiotics may significantly impact cardiovascular health, particularly certain Lactobacillus species, such as Lactobacillus reuteri GMNL-263 (Lr263) probiotics, which have been shown to reduce obesity and arteriosclerosis in vivo. In the present study, we examined the potential of heat-killed bacteria to attenuate high fat diet (HFD)-induced hepatic and cardiac damages and the possible underlying mechanism of the positive effects of heat-killed Lr263 oral supplements. Heat-killed Lr263 treatments (625 and 3125 mg/kg-hamster/day) were provided as a daily supplement by oral gavage to HFD-fed hamsters for eight weeks. The results show that heat-killed Lr263 treatments reduce fatty liver syndrome. Moreover, heat-killed Lactobacillus reuteri GMNL-263 supplementation in HFD hamsters also reduced fibrosis in the liver and heart by reducing transforming growth factor β (TGF-β) expression levels. In conclusion, heat-killed Lr263 can reduce lipid metabolic stress in HFD hamsters and decrease the risk of fatty liver and cardiovascular disease.     

Magnetic Resonance Signal Amplification by Reversible Exchange of Selective PyFALGEA Oligopeptide Ligands Towards Epidermal Growth Factor Receptors

The biorelevant PyFALGEA oligopeptide ligand, which is selective towards the epidermal growth factor receptor (EGFR), has been successfully employed as a substrate in magnetic resonance signal amplification by reversible exchange (SABRE) experiments. It is demonstrated that PyFALGEA and the iridium catalyst IMes form a PyFALGEA:IMes molecular complex. The interaction between PyFALGEA:IMes and H₂ results in a ternary SABRE complex. Selective 1D EXSY experiments reveal that this complex is labile, which is an essential condition for successful hyperpolarization by SABRE. Polarization transfer from parahydrogen to PyFALGEA is observed leading to significant enhancement of the ¹H NMR signals of PyFALGEA. Different iridium catalysts and peptides are inspected to discuss the influence of their molecular structures on the efficiency of hyperpolarization. It is observed that PyFALGEA oligopeptide hyperpolarization is more efficient when an iridium catalyst with a sterically less demanding NHC ligand system such as IMesBn is employed. Experiments with shorter analogues of PyFALGEA, that is, PyLGEA and PyEA, show that the bulky phenylalanine from the PyFALGEA oligopeptide causes steric hindrance in the SABRE complex, which hampers hyperpolarization with IMes. Finally, a single-scan ¹H NMR SABRE experiment of PyFALGEA with IMesBn revealed a unique pattern of NMR lines in the hydride region, which can be treated as a fingerprint of this important oligopeptide.     

Comprehensive numerical study of molecular diffusion effects and Eddy Dissipation Concept model in MILD combustion

Moderate or Intense Low-oxygen Dilution (MILD) combustion is a clean combustion technology with high thermal efficiency and low levels of emissions. In this paper, by employing Adelaide Jet-in-Hot-Co-flow (AJHC), several approaches are examined to increase the numerical solution accuracy. First, molecular diffusion effects are investigated in MILD combustion. Second, adjusting the Eddy Dissipation Concept (EDC) coefficients is comprehensively discussed, and finally, the reaction fraction coefficient and EDC formulation are investigated. The results show that the effect of enthalpy transport caused by molecular diffusion on the energy equation must be considered in the low oxygen concentration regions. Also, the maximum temperature in the MILD region can be kept constant by adjusting EDC coefficients. Furthermore, it is shown that applying the reaction fraction factor increases the accuracy of the numerical solution in the MILD region.